澳门历史开奖记录

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Like many of UCL's Life Sciences departments today, Structural and Molecular Biology can trace its roots back to UCL's Department of Physiology. The department was the first of its type in England when it was first created听in 1828. As the university's knowledge in this area grew, provisions were made for sub-areas of interest.听
The establishment 澳门历史开奖记录 of Biochemistry as a truly independent discipline was a gradual process. What today would be considered to be biochemistry began in 1901 with the establishment of a post of Assistant in Physiological Chemistry within the then Institute of Physiology. At the end of the 1914-18 war, the College considered itself to be the only college or university in the UK that had instituted definite courses in Biochemistry 鈥 although only for medical students.
A desire to continue to lead the country in the field of Biochemistry led the College in 1922 to establish a Chair in Biochemistry supported by part of an endowment from the Rockefeller Foundation for a Department of Intermediate Medical Studies. For the next decade or so the UCL Biochemical Laboratory, headed by its newly-established Chair, continued to be part of the Institute of Physiology under the general direction of the Jodrell Professor of Physiology.
In 1934, during a reorganization of the Medical Faculty, a new Department of Physiology, Pharmacology and Biochemistry was created. At the end of 1945 this composite department was dissolved into three separate departments though it is likely that the biochemists had achieved de facto independence from the mid-1930s onwards as evidenced by their research publications tending to just carry the address Department of Biochemistry.
Even after the autonomous Department of Biochemistry came into being at the beginning of 1946 it continued to have no degree programmes of its own with its teaching remaining, as it had been for many years, confined to preclinical medical and dental students.听
It was the early 1950s before the department was offering MSc and BSc programmes in Biochemistry and it was the very late 1950s into the early 1960s before the Department of Biochemistry escaped from cramped accommodation in the basement of the Physiology/Pharmacology building and moved to occupy newly-built space in what is now the Darwin Building.听

Brief Biographies of the Leaders of Biochemistry 澳门历史开奖记录

Robert Plimmer

Although he was never a professor or head of department 澳门历史开奖记录 Plimmer can certainly be regarded as the 鈥楩ounder鈥 UCL biochemist.听In 1901 a post of Assistant in Physiological Chemistry had been established within the UCL Physiology department and Plimmer was appointed to this in 1904, eventually becoming the first Reader in Physiological Chemistry.
During the 1914-18 war Plimmer was attached to the Directorate of Hygiene at the War Office. As Captain Plimmer he made a series of analyses on the commoner foodstuffs for the Army Medical Authorities, many of these performed in his laboratory 澳门历史开奖记录. Thereafter his lifelong research interests centered around the chemistry of proteins and of biological phosphorous compounds together with many aspects of nutrition and vitamins 鈥 topics on which he wrote many articles for magazines and periodicals, with 49 research papers listed by Pubmed with him as an author between 1904 and 1941 contributing to that output.
plimmer_book

Biochemists of his generation particularly remembered him for being, together with J.A. Gardner, a co-founder in 1911 of the Biochemical Club which became the Biochemical Society in 1913 with Plimmer as its first honorary secretary until 1919. The first official meeting was held in the Physiology Department 澳门历史开奖记录 on 4th March 1911 and until 1968 the annual general meetings of the Biochemical Society were always held 澳门历史开奖记录.
For many years he has been commemorated through the Plimmer Prize which is one of the two college prizes that are awarded annually to the best second year students in the UCL Biochemistry and Biochemistry-related BSc programmes.

Jack Drummond

In 1919, following the resignation of Plimmer, was invited by Professor Ernest Starling to move to UCL. Initially he was听a research assistant, becoming Reader in Physiological Chemistry in 1920 and in 1922 at the early age of thirty-one he was appointed to the newly-created Chair of Biochemistry at the college. Until the outbreak of war in 1939 he investigated the chemistry and action of vitamins 鈥 in particular the fat soluble vitamins A and D 鈥 together with many other aspects of human nutrition, his scientific output comprising 183 publications between 1914 and 1948.

Jack Drummond

Drummond was keen to apply the new science of nutrition and began a study of the English diet over the last 500 years. The study was published as听in 1939 and was considered to be ground-breaking. The book is still in print today.
the_englishmans_food
When the war broke out in 1939, Drummond was appointed chief advisor on food contamination. In 1940 he was appointed Scientific Advisor to the Ministry of Food. He produced a plan for the distribution of food based on "sound nutritional principles". He believed that his system of rationing would not only maintain the nation's health but improve it and he was correct.听
Follow up studies showed that the population's health improved under rationing and it is commonly believed that to this day this period of time was when the health of the people of the United Kingdom was at its best.听

Jack Drummond

Drummond left UCL in 1945 to take a role with听听as Director of Research. Unfortunately, Drummond, his wife and his 10-year-old daughter were murdered in France in 1952.
Today the Drummond Prize is awarded annually to the best second-year students in the UCL Biochemistry and Biochemistry-related BSc programmes.

Margaret Kerley

Between 1927 and 1931 Margaret Kerley听undertook research within the Department of Physiology and Biochemistry 澳门历史开奖记录 for which she was awarded a PhD in 1931.听Between 1931 and 1933 she worked with the future Nobel laureates Carl and Gerty Cori at the Washington University School of Medicine in St. Louis. On her return to the UK in 1933 she re-established her association with UCL as firstly Assistant Lecturer then Lecturer and subsequently Senior Lecturer, being appointed Reader in Biochemistry in 1949.
Her research publications (28 listed by Pubmed with her as author between 1930 and 1971) were almost entirely devoted to aspects of carbohydrate and amino acid metabolism with particular interest in those in the retina and the liver.
A generous bequest in her will allowed UCL to establish the annual Margaret Kerley Prize that she wished to be awarded 鈥渢o the most deserving first-year Biochemistry BSc student(s)鈥.

Frank Young

After the war Biochemistry 澳门历史开奖记录 was taken over by who went on to be knighted in 1973. He led the department from 1945 to 1949.听
In January 1946 UCL Biochemistry finally became an autonomous department with Young at its head. His major priority was to establish a BSc programme in Biochemistry.
Although he did not achieve this during his short tenure he did succeed in getting an MSc programme started which became a gateway through which several distinguished biochemists have entered the subject; to name but a few: , (a future head of UCL Biochemistry), (the first Head of Biochemistry at Dundee and subsequently Chief Executive of the Institute of Cancer Research) and one of Young鈥檚 own sons who became Professor of Neurochemistry at McGill University.

Frank Young

Ernest Baldwin

听In 1950 succeeded Young as Professor and Head of the Biochemistry department 澳门历史开奖记录. There he was able to fulfill Young鈥檚 ambition of the establishment of a BSc programme in Biochemistry 鈥 the first in the University of London. The programme began with three students in 1953 and soon rapidly expanded.

Ernest Baldwin

In 1937 Baldwin听published a small book, Comparative Biochemistry which became recognized as a classic introduction to that subject. In 1947 he published . In many respects this was the first modern textbook of biochemistry, providing a lucid description of metabolic interactions and taking biochemistry out of the age of natural products chemistry and of purely medical and physiological chemistry. The book was translated into many languages eventually running into five editions and in 1952 gaining Baldwin the European Cortina-Ulisse Prize of one million Italian lire.

Prakash Datta

Datta read for a BSc in Chemistry 澳门历史开奖记录 and subsequently read Medicine at University College Hospital Medical School. He then joined the staff of the UCL Department of Biochemistry. Datta played a major role in setting up the (FEBS) in the late 1960s. He devoted considerable time to FEBS over his career and was both its treasurer and the managing editor of its journal

His 54 research publications between 1949 and 1966 covered a range of topics, mainly in the area of physical biochemistry with particular emphasis on measurements of acid dissociation constants of biological molecules and the stability constants of metal complexes with the same.

Bob Rabin

graduated with a BSc from the UCL Department of Chemistry in 1951 and then moved into the UCL Biochemistry department where he graduated from the MSc programme in 1952 and was awarded a PhD in 1956.听Within the UCL Biochemistry department he was firstly appointed as Assistant Lecturer (1954) and then Lecturer (1957), Reader (1963) and Professor of Ezymology (1967).

In 1970 he was appointed Head of the department 鈥 a post he held until 1988. His early research, frequently in collaboration with Prakash Datta and Eric Crook, was largely devoted to studies of proton and metal ion binding to peptides and proteins.

The late 1950s and early 1960s saw him launch into investigations of the catalytic mechanisms of several enzymes 鈥 in particular pancreatic ribonuclease. Together with Tony Mathias and others a chemical mechanism for the ribonuclease reaction was put forward following an inspired piece of chemical intuition well before the crystal structure of the enzyme was solved.

This was the very first deduction of the catalytic mechanism of an enzyme and, although some refinements have subsequently been added, it has stood the test of time and its basic characteristics are still accepted.

In all PubMed lists 101 publications with Bob Rabin听as author between 1954 and 1995.

Leaders of UCL Biochemistry from 1904 to present:

Leaders of UCL Biochemistry from 1904 to present
Robert Plimmer1904-1919
Jack Drummond1922-1945
Margaret Kerley1939-1945
Frank Young1945-1949
Ernest Baldwin1950-1969
Prakash Datta1969-1970
Bob Rabin1970-1988
Peter Butterworth1988-1990
Michael Rosemeyer1990-1992
Michael Waterfield1992-2001
David Saggerson2001-2006
Gabriel Waksman2006-2019
Snezana Djordjevic2019-

Read more about the leaders of UCL Biochemistry听

More SMB Research Achievements

joined what was known at the time as the Department of Biochemistry and Molecular Biology in 1995. She had done her PhD in UCL's biochemistry department in the mid 1970s in an enzymology lab headed by the late Michael Holloway.听听

She is best known for her research that analyses genes, proteins and biological systems using听computational methods听to听classify proteins into evolutionary families.听As of the end of 2021,听her has taken 151 million protein domains and classified them into 5,481 superfamilies. She is also the first woman to serve as president of the

Christine Orengo


In 2003, UCL and Birkbeck co-founded the 听to promote multi-disciplinary research at the interface of structural-, computational- and chemical biology. The institute aims to break the traditional boundaries between structural, molecular and cell biology. It uses both multi-disciplinary approaches aimed to bridge across the scales of biology and methods to integrate disparate data across the disciplines.听听

Gabriel Waksman joined UCL in 2003听to take up the听Joint Chair of Structural Molecular Biology at University College London and Birkbeck College London.听Gabriel discovered the structure and function of the type IV secretion mechanism in bacteria, which is responsible for the sharing of genetic material 鈥 including antibiotic resistance genes 鈥 between bacteria. Gabriel鈥檚 work provides the basis for the design of new compounds to block secretion and thus prevent the spread of antibiotic resistance.听听

Gabriel Waksman

Jo Santini joined SMB from Australia听in 2006. In 2018, she announced the creation of a low-cost, easy-to-use arsenic sensor to test drinking water. According to the World Health Organisation, 140 million people worldwide drink water containing unsafe levels of arsenic. She also set up Microbiology@UCL,听a consortium of researchers with interests in microbiology across a wide range of faculties, schools, institutes and partner organisations.

Jo Santini

Some of our Notable Graduates听

  • completed both听his BSC and PhD in the department. Cohen went on to听become the head of the MRC Protein Phosphorylation Unit and Director of the Wellcome Trust Biocentre at the University of Dundee.
  • completed both听her BSC and PhD in the department. She has achieved scientific distinction at the MRC Laboratory of Molecular Biology in Cambridge.
  • completed听his BSc in the department and PhD in the Crystallography department at Birkbeck College. Later he was a member of staff of the UCL Department of Biochemistry and听then moved to the Institute of Cancer Research in London. He subsequently became Dean of Life Sciences at the University of Sussex.
  • completed both听his BSc and PhD in the department. He joined the Scientific Civil Service and rose to become Chief Executive, Central Science Laboratory Agency.
  • completed both听his BSC and PhD in the department. He went on to become a听Professor of Plant Biochemistry at the University of Edinburgh.

Notable Department Staff

  • was a member of the Biochemistry staff from 1953 to 1963. He went on to听become a Professor of Neurobiology at Stanford University, USA.
  • was a Professor of Bioinformatics in the department. She went on to be the听Director of the European Bioinformatics Institute in Cambridge.
  • was a Professor of Microbiology in the department for many years. She went on to become a Vice-president of the Royal Society.
  • was associated with the department through being director of the MRC Laboratory of Cell Biology 澳门历史开奖记录. He moved to New York and became a Professor and Chair of the Cell Biology department at the Sloane-Kettering Institute.
  • is a biochemist who worked as an MRC Research Professor 澳门历史开奖记录 until 2016.听