Description
This module focuses on the mechanism of cancer generation and progression and on the range of treatment options. Starting with a background integrating genetic, cellular, and molecular aspects, it covers recent cancer research leading to a general conceptual framework for the development of this disease. The module also provides insights and illustrations from specific cancer types and concludes with a variety of established and emerging treatments. The overall aim of this module is to provide a strong background for careers related to basic cancer research, experimental medicine, and drug discovery.
Indicative lecture list:
Properties of transformed cells
Cell division and cell cycle
Cellular senescence and immortalisation
Oncogenic subversion and signal transduction
Tumour suppressor genes
Angiogenesis in cancer
Cancer metabolism
Cancer stem Cells
The role of metastasis in cancer
Intratumour heterogeneity, tumour evolution and clinical implications
Epithelial cancer: breast cancer
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Novel therapeutics
Targeted cancer therapy
Exploiting DNA damage response in cancer therapy
Module deliveries for 2024/25 academic year
Last updated
This module description was last updated on 19th August 2024.
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